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基本資料
姓名 劉奕方
職稱 助理教授
辦公室分機 02 2905 3613
實驗室分機 02 2905 3612
E-mail 070647@mail.fju.edu.tw
專長
  • 微量營養素營養與代謝（鐵、碘、鋅）
  • 鐵代謝、粒線體生物學與RNA（tRNA, rRNA, miRNA）調控
  • 營養監測、生物標誌與營養風險評估
  • 礦物質DRIs研修、營養強化與營養政策
  • 永續營養與飲食行為研究
研究方向
  • 1. 微量營養素營養與代謝
  • 2. 營養監測與生物標誌
  • 3. 營養強化與政策研究
  • 4. 營養流行病學與實證營養
  • 5. 永續營養與健康促進
  • 6. 食物份量影像建置與數位營養工具
  • 7. 細胞與分子營養學
主要學歷
  • 台灣大學微生物與生化學研究所營養科學組博士
  • 台灣大學農業化學研究所營養科學組碩士
  • 台灣大學農業化學系農產製造組學士
學術研究成果
  • 學術期刊論文
  • 1. Wang YM, Liew YF, Chang KY, Tsai IH. Purification and characterization of the venom phospholipases A2 from Asian monotypic crotalinae snakes. J Nat Toxins. 1999 Oct;8(3):331-40.
  • 2. Liew YF, Shaw NS. Mitochondrial cysteine desulfurase iron-sulfur cluster S and aconitase are post-transcriptionally regulated by dietary iron in skeletal muscle of rats. J Nutr. 2005 Sep;135(9):2151-8. doi: 10.1093/jn/135.9.2151.
  • 3. Wang SJ, Chou SH, Kuo YC, Chou SS, Tzeng WF, Leu JY, Huang RF, Liew YF.HDT-1, a new synthetic compound, inhibits glutamate release in rat cerebral cortex nerve terminals (synaptosomes). Acta Pharmacol Sin. 2008 Nov;29(11):1289-95. doi: 10.1111/j.1745-7254.2008.00882.x.
  • 4. Chou SH, Chou SS, Liew YF, Leu JY, Wang SJ, Huang RF, Tzeng WF, Kuo YC. A new synthetic compound, 2-OH, enhances interleukin-2 and interferon-gamma gene expression in human peripheral blood mononuclear cells. Molecules. 2009 Jul 2;14(7):2345-55. doi: 10.3390/molecules14072345.
  • 5. SC Ho, YL Tang, SM Lin, YF Liew. Evaluation of peroxynitrite-scavenging capacities of several commonly used fresh spices. Food Chem. 2010 Apr. 1; 119(3):1102-1107. Doi: 10.1016/j.foodchem.2009.08.020
  • 6. Liew YF, Huang CT, Chou SS, Kuo YC, Chou SH, Leu JY, Tzeng WF, Wang SJ, Tang MC, Huang RF. The isolated and combined effects of folic acid and synthetic bioactive compounds against Abeta(25-35)-induced toxicity in human microglial cells. Molecules. 2010 Mar 11;15(3):1632-44. doi: 10.3390/molecules15031632.
  • 7. Lin TY, Lu CW, Huang SK, Chou SS, Kuo YC, Chou SH, Tzeng WF, Leu CY, Huang RF, Liew YF, Wang SJ.HTDP-2, a new synthetic compound, inhibits glutamate release through reduction of voltage-dependent Ca²⁺ influx in rat cerebral cortex nerve terminals. Pharmacology. 2011;88(1-2):26-32. doi: 10.1159/000328774. Epub 2011 Jul 1.
  • 8. 潘富子、尉遲浤圳、劉奕方、許瑞芬。親子代葉酸營養攝取量對子代C57BL/6小鼠生長與肺組織癌化及發炎調轉能量代謝訊息傳遞分子表現之影響。Nutr Sci J, 2016, Vol. 41, No. 3, pp.75~84。
  • 9. 藍文妤、林立倫、尉遲浤圳、劉奕方、許瑞芬。葉酸補充調節慢性腸炎誘導惡性結腸腫瘤發展及癌幹細胞指印分子表現性。Nutr Sci J, 2019, Vol. 43, No. 3, pp.74~85 74 DOI: 10.6691/NSJ.201909_43(3).0002。
  • 10. Jing-Yao Zhang, Hui-Chen Lo, Feili Lo Yang, Yi-Fang Liu, Wen-Mein Wu, Chi-Chun Chou Plant-Based, Antioxidant-Rich Snacks Elevate Plasma Antioxidant Ability and Alter Gut Bacterial Composition in Older Adults. Nutrients. 2021;13(11):3872. doi: 10.3390/nu13113872.
  • 11. Tsao CW, Liao YR, Chang TC, Liew YF, Liu CY. Effects of Iron Supplementation on Testicular Function and Spermatogenesis of Iron-Deficient Rats. Nutrients. 2022 May 14;14(10):2063. doi: 10.3390/nu14102063.
  • 12. Huang A, Huang SY, Shah P, Ku WC, Huang KT, Liu YF, Su CL, Huang RS. Suboptimal folic acid exposure rewires oncogenic metabolism and proteomics signatures to mediate human breast cancer malignancy. J Nutr Biochem. 2022 Aug;106:109000. doi: 10.1016/j.jnutbio.2022.109000. Epub 2022 Apr 20.
  • 13. Chen WJ, Huang SY, Chen YW, Liu YF, Huang RS. Dietary Folate Deficiency Promotes Lactate Metabolic Disorders to Sensitize Lung Cancer Metastasis through MTOR-Signaling-Mediated Druggable Oncotargets. Nutrients. 2023 Mar 21;15(6):1514. doi: 10.3390/nu15061514.
  • 14. Liu YF, Wu YC, Yang Y, Lo HC. Soy Protein and Safflower-Seed Oil Attenuate Inflammation and Immune Dysfunction in Rats with Hyperuricemia. Int J Mol Sci. 2024 Dec 3;25(23):12977. doi: 10.3390/ijms252312977.
  • 15. YF Liu, XZ Chen,LY Yang and CK Wang. Determinants of Iodine Insufficiency in Taiwanese Adults: Evidence from NAHSIT 2017-2020 on Eating-out Behaviours and Iodine-Rich Food Consumption. BIO Web of Conferences 187, 01006 (2025) https://doi.org/10.1051/bioconf/202518701006.
  • 16. 劉奕方、張美鈴、陳顯宗、蕭寧馨。利用台灣國民營養與健康狀況變遷調查2013-2016數據探討國人之血紅素健康範圍與貧血標準參考值。Nutr Sci J, 2025, Vol. 49, No. 2, pp.38~52 DOI: 10.6691/NSJ.202506_49(2).0001。
  • 17. Joy C, Chiang YC, Ko WH, Liu YF. Development and Psychometric Validation of a Knowledge, Attitudes, and Practices (KAP) Questionnaire on Sustainable Diets in Taiwan. Nutrients. 2026 Mar 13;18(6):908. doi: 10.3390/nu18060908.
實驗室成員或活動照片
其他

營養轉譯與健康促進研究室

Translational Nutrition and Health Promotion Laboratory (TNHP Lab)

(前身：分子營養研究室 / Formerly Molecular Nutrition Laboratory)

 

研究簡介（Research Overview）

本研究室致力於整合基礎營養科學、人體營養研究、營養監測及健康促進，建立由實驗室至社區（Bench-to-Community）的轉譯營養研究架構，將科學證據轉化為改善國人營養與健康之實務應用。

The Translational Nutrition and Health Promotion Laboratory is dedicated to integrating basic nutrition science, human nutrition research, nutrition surveillance, and health promotion. Our mission is to establish a bench-to-community translational nutrition framework that bridges scientific discovery and practical applications to improve nutritional status and public health.

研究主題涵蓋微量營養素營養與代謝、營養生物標誌、國民營養監測、礦物質膳食營養素參考攝取量（DRIs）、食品營養強化策略、營養政策及健康促進研究。研究方法結合細胞培養、動物模式、人體研究、營養流行病學及政策分析，建立從基礎研究到政策應用之完整科學證據鏈。

Our research encompasses micronutrient nutrition and metabolism, nutritional biomarkers, population nutrition surveillance, mineral Dietary Reference Intakes (DRIs), food fortification strategies, nutrition policy, and health promotion. By integrating cell culture models, animal studies, human nutrition research, nutritional epidemiology, and policy analysis, we aim to generate scientific evidence that supports nutrition practice and public health decision-making.

 

研究專長（Research Expertise）

  • 微量營養素營養與代謝（鐵、碘、鋅）

Micronutrient Nutrition and Metabolism (Iron, Iodine, and Zinc)

  • 鐵代謝、粒線體生物學與非編碼RNA（tRNA、rRNA、miRNA）調控

Iron Metabolism, Mitochondrial Biology, and Non-coding RNA (tRNA, rRNA, and miRNA) Regulation

  • 營養監測、生物標誌與營養風險評估

Nutrition Surveillance, Nutritional Biomarkers, and Nutritional Risk Assessment

  • 礦物質DRIs研修、營養強化與營養政策

Mineral Dietary Reference Intakes (DRIs), Nutrition Fortification, and Nutrition Policy

  • 永續營養與飲食行為研究

Sustainable Nutrition and Dietary Behavior Research

 

研究特色（Research Highlights）

  • 鐵、碘及鋅營養研究

Iron, Iodine, and Zinc Nutrition Research

  • Ferritin、Hemoglobin及Urinary Iodine等營養生物標誌研究

Nutritional Biomarker Research, including Ferritin, Hemoglobin, and Urinary Iodine

  • 國民營養健康狀況變遷調查（NAHSIT）資料分析與應用

Analysis and Application of Taiwan Nutrition and Health Survey (NAHSIT) Data

  • 礦物質膳食營養素參考攝取量（DRIs）研修

Development and Revision of Mineral Dietary Reference Intakes (DRIs)

  • 碘、鐵及鋅營養強化策略研究

Iodine, Iron, and Zinc Fortification Strategies

  • 永續飲食、KAP及COM-B行為研究

Sustainable Diets, KAP Studies, and COM-B Behavioral Research

  • 營養教育與健康促進介入研究

Nutrition Education and Health Promotion Interventions

 

研究室願景（Laboratory Vision）

本研究室致力於透過轉譯營養科學研究，建立從基礎研究、人體研究、營養監測到營養政策與健康促進之完整科學證據鏈，促進國民營養與健康福祉。

The laboratory is committed to advancing translational nutrition research by establishing a comprehensive evidence chain spanning from basic science and human studies to nutrition surveillance, nutrition policy, and health promotion, ultimately improving nutritional well-being and public health.

 

研究室座右銘（Laboratory Motto）

From Bench to Policy, From Nutrition to Health

從基礎研究到營養政策，從營養科學到健康促進。